Roughly half of HFrEF patients, screened by polysomnography, have clinically significant sleep-disordered breathing. The phenotype is usually mixed: Heart failure and sleep-disordered breathing share a bidirectional relationship with meaningful prescribing consequences. A patient with heart failure with reduced ejection fraction (HFrEF, LVEF ≤ 45%) is likely to CPAP therapy for heart failure exhibit some combination